Single Antibody Detection of T-Cell Receptor αβ Clonality by Flow Cytometry Rapidly Identifies Mature T-Cell Neoplasms and Monotypic Small CD8-Positive Subsets of Uncertain Significance.

Min ShiDragan JevremovicGregory E OttesonMichael M TimmHoratiu OlteanuPedro Horna

Published in: Cytometry. Part B, Clinical cytometry (2019)

Inclusion of a single anti-TRBC1 antibody into a diagnostic T-cell flow cytometry panel facilitates the rapid identification of T-cell neoplasms, in addition to small monotypic CD8-positive subsets of uncertain significance. © 2019 International Clinical Cytometry Society.

Keyphrases

flow cytometry
loop mediated isothermal amplification
peripheral blood
nk cells
single cell
genome wide
gene expression
dna methylation
bioinformatics analysis
binding protein