Sequential ctDNA whole-exome sequencing in advanced lung adenocarcinoma with initial durable tumor response on immune checkpoint inhibitor and late progression.
Etienne Giroux-LeprieurZofia Hélias-RodzewiczPaul Takam KamgaAdrien CostantiniCatherine JulieAlexandre CorjonCoraline DumenilJennifer DumoulinViolaine GiraudSylvie LabruneSimon GarinetThierry ChinetJean-François EmilePublished in: Journal for immunotherapy of cancer (2021)
This is the first study describing putative molecular mechanisms associated with late progression under ICI in lung cancer. Studies on treatment strategies adapted to these mechanisms are needed.
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