Plasma Cell-Free DNA Integrity Assessed by Automated Electrophoresis Predicts the Achievement of Pathologic Complete Response to Neoadjuvant Chemotherapy in Patients With Breast Cancer.

Gabriella CirmenaLorenzo FerrandoFrancesco RaveraAnna GarutiMartina DameriMaurizio GalloValentina BarberoFabio FerrandoLucia Del MastroAlessandro GarlaschiDaniele Friedman Piero FregattiAlberto BallestreroFrancesco Ravera

Published in: JCO precision oncology (2022)

cfDI index measured after NACT completion shows great potential in the assessment of pCR in patients with BC. The evaluation of its use in combination with MRI is strongly warranted in prospective studies.

Keyphrases

neoadjuvant chemotherapy
locally advanced
lymph node
sentinel lymph node
contrast enhanced
magnetic resonance imaging
deep learning
machine learning
high throughput
case control
rectal cancer
diffusion weighted imaging
squamous cell carcinoma
radiation therapy
human health
early stage