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The research landscape of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND)-a comprehensive scoping review.

Stephanie VancloosterStacey BissellAgnies M van EeghenNola ChambersLiesbeth De WaeleAnna W ByarsJamie K CapalSebastián CukierPeter E DavisJennifer FlinnSugnet Gardner-LubbeTanjala GipsonTosca-Marie HeunisDena HookJ Christopher KingswoodDarcy A KruegerAubrey J KummMustafa SahinEva SchoetersCatherine SmithShoba SrivastavaMegumi TakeiRobert WaltereitAnna C JansenPetrus J de Vries
Published in: Journal of neurodevelopmental disorders (2022)
Despite the recent increase in TAND research, studies that represent participants across the lifespan, LMIC research sites and non-pharmacological interventions were identified as future priorities. The quality of cohort studies requires improvement, to which the use of standardised direct behavioural assessments may contribute. In human studies, the academic level in particular warrants further investigation. Remote technologies could help to address many of the TAND knowledge gaps identified.
Keyphrases
  • endothelial cells
  • case control
  • healthcare
  • current status
  • induced pluripotent stem cells
  • single cell
  • medical students
  • drosophila melanogaster