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Phylogeny-guided microbiome OTU-specific association test (POST).

Caizhi HuangBenjamin J CallahanMichael C WuShannon T HollowayHayden BrochuWenbin LuXinxia PengJung-Ying Tzeng
Published in: Microbiome (2022)
Using POST, we show that adaptively leveraging the phylogenetic information can enhance the selection performance of associated microbiome features by improving the overall true-positive and false-positive detection. We developed a user friendly R package POSTm which is freely available on CRAN ( https://CRAN.R-project.org/package=POSTm ). Video Abstract.
Keyphrases
  • healthcare
  • label free
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  • real time pcr
  • social media