Mutant selection window of clarithromycin for clinical isolates of Helicobacter pylori.
Zi-Han FengLing FanJing YangXing-Yue HuoYan GuoYi ZhangChun-Hui LanPublished in: BMC microbiology (2019)
This study showed that in the clarithromycin-sensitive clinical isolates of H. pylori, low-dose clarithromycin may lead to decreased drug sensitivity or even clarithromycin resistance; strains with a 0.25 mg/L MIC display a high risk of treatment failure.