High-normal estimated glomerular filtration rate and hyperuricemia positively correlate with metabolic impairment in pediatric obese patients.
Roberta RicottiGiulia GenoniEnza GiglioneAlice MonzaniMartina NugnesSara ZanettaMatteo CastagnoAgostina MaroldaGiorgio BellomoGianni BonaSimonetta BelloneFlavia ProdamPublished in: PloS one (2018)
A worse cardiometabolic profile was observed in subjects with an eGFR > 1 SD compared to other subgroups. Therefore, pediatric obese patients with eGFR > 1 SD or hyperuricemia should be closely monitored for microalbuminuria and post-challenge glucose and insulin secretion, all potential indicators of renal dysfunction in these young patients.
Keyphrases
- obese patients
- small cell lung cancer
- bariatric surgery
- end stage renal disease
- epidermal growth factor receptor
- tyrosine kinase
- ejection fraction
- chronic kidney disease
- roux en y gastric bypass
- uric acid
- newly diagnosed
- gastric bypass
- weight loss
- type diabetes
- metabolic syndrome
- adipose tissue
- blood pressure
- blood glucose
- insulin resistance
- risk assessment
- middle aged