High prevalence of short telomeres in idiopathic porto-sinusoidal vascular disorder.
Alexander CoukosChiara SagliettiChristine SempouxMonika HaubitzThomas GreuterLaureane Mittaz-CrettolFabienne MaurerElise Mdawar-BaillyDarius MoradpourLorenzo AlberioJean-Marc GoodGabriela M BaerlocherMontserrat FragaPublished in: Hepatology communications (2024)
Short and very short telomeres were highly prevalent in patients with idiopathic PSVD, with 31% presenting with variants in telomere-related genes. Telomere biology may play an important role in vascular liver disease development. Clinicians should consider measuring telomeres in any patient presenting with PSVD.