Clinical Value of Serum Levels of 11-Oxygenated Metabolites of Testosterone in Women With Polycystic Ovary Syndrome.

Flavia TosiMichela VillaniSabrina GarofaloGiulia FaccinEnzo BonoraTom FiersJean-Marc KaufmanPaolo Moghetti

Published in: The Journal of clinical endocrinology and metabolism (2022)

Serum levels of 11-oxygenated androgens are higher in women with PCOS than in controls. However, these hormones show a poor performance in recognizing women with hyperandrogenism, as currently defined. The relationships of these androgens with insulin sensitivity strongly differ from that of FT, suggesting a different role of classic and 11-oxygenated androgens in the pathophysiology of PCOS.

Keyphrases

polycystic ovary syndrome
insulin resistance
ms ms
replacement therapy
type diabetes
metabolic syndrome
smoking cessation