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From primal scenes to synthetic cells.

H A E Hub Zwart
Published in: eLife (2019)
Synthetic cells spark intriguing questions about the nature of life. Projects such as BaSyC (Building a Synthetic Cell) aim to build an entity that mimics how living cells work. But what kind of entity would a synthetic cell really be? I assess this question from a philosophical perspective, and show how early fictional narratives of artificial life - such as the laboratory scene in Goethe's Faust - can help us to understand the challenges faced by synthetic biology researchers.
Keyphrases
  • induced apoptosis
  • living cells
  • single cell
  • cell cycle arrest
  • cell therapy
  • endoplasmic reticulum stress
  • oxidative stress
  • single molecule
  • quality improvement
  • bone marrow