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Incontinentia pigmenti Stage 1 is not simply vesiculo-bullous but vesiculo-pustular.

Tubanur ÇetinarslanRegina Fölster-HolstDirk van GyselMatthias BuchnerRudolf Happle
Published in: Pediatric dermatology (2024)
Incontinentia pigmenti (IP) is a rare X-linked dominant, male-lethal disorder characterized by pathognomic skin lesions. As described in the literature the typical cutaneous changes follow the pattern of Blaschko's lines and develop in four stages that usually start at birth. Stage 1 is called vesicular, bullous or inflammatory. The vesicles are rapidly filled with eosinophils and thus turn into pustules. Thus, the term "pustular" is relevant to the first phase of IP, and the stage can be considered as "vesiculopustular/inflammatory" to be more precise than "vesicular" or "bullous."
Keyphrases
  • oxidative stress
  • systematic review
  • gestational age
  • preterm infants
  • pregnant women
  • preterm birth