Effect of maternal oxytocin on umbilical venous and arterial blood flows during physiological-based cord clamping in preterm lambs.
Fiona J StenningGraeme R PolglaseArjan B Te PasKelly J CrossleyMartin KluckowAndrew W GillEuan Morrison WallaceErin V McGillickCorinna BinderDouglas A BlankCalum RobertsStuart B HooperPublished in: PloS one (2021)
We found no evidence that amplification of uterine contractions with oxytocin increase placental transfusion during DCC. Instead they decreased both UA and UV flow and caused a net loss of blood from the lamb. Uterine contractions did, however, have significant cardiovascular effects and reduced systemic and cerebral oxygenation.