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Imperatorin derivative OW1, a new vasoactive compound, attenuates cell proliferation and migration by inhibiting Nox1-mediated oxidative stress.

Nan ZhouSuyun YongXianpeng ShiPeng ZhangJian-Hua Wang
Published in: The Journal of pharmacy and pharmacology (2023)
OW1 may inhibit vascular remodelling by downregulating the Nox1-ROS-MAPK/MMP signalling pathway.
Keyphrases
  • oxidative stress
  • reactive oxygen species
  • signaling pathway
  • dna damage
  • single cell
  • cell therapy
  • cell death
  • pi k akt
  • diabetic rats
  • cell migration
  • stem cells
  • mesenchymal stem cells
  • endoplasmic reticulum stress