Oxygenated machine perfusion at room temperature as an alternative for static cold storage in porcine donor hearts.
Vincent van SuylenKatrien VandendriesscheArne NeyrinckFoppe NijhuisArjan van der PlaatsErik K VerbekenPieter VermeerschBart MeynsMassimo A MarianiFilip R RegaMichiel E ErasmusPublished in: Artificial organs (2021)
We conclude that the initial functional outcome of MP-preserved hearts was transiently superior compared to CS, with no histological injury post-Langendorff. Our machine perfusion strategy could offer feasible and safe storage of hearts prior to transplantation. Future studies are warranted for further optimization.