Calibration of cell-free DNA measurements by next-generation sequencing.

Derek L HoerresQunsheng DaiSandra ElmoreSiddharth ShethGaorav P GuptaSunil KumarMargaret L Gulley

Published in: American journal of clinical pathology (2023)

Our novel strategy for calibrating NGS assays suggests potential for a universal reference material to overcome biological and preanalytical variables hindering traditional NGS strategies for quantifying disease burden.

Keyphrases

high throughput
copy number
circulating tumor
risk factors
human health
dna methylation
low cost
risk assessment
climate change