Characterization of polymeric phenolic acids and flavonoids in Clerodendranthi Spicati Herba using ultrahigh-performance liquid chromatography coupled to quadrupole time-of-flight tandem mass spectrometry with target and nontarget data mining strategy.
Yun LuoQuan WenChang-Jiang-Sheng LaiYulin FengBaolian MaPublished in: Rapid communications in mass spectrometry : RCM (2020)
The results indicated that the UHPLC/QTOF-MS/MS method coupled with target and nontarget data mining strategy was feasible and rational for identifying the polymeric phenolic acids and flavonoids in complex chemical constituents of CSH. The findings will be conducive to the discovery of the active ingredients of CSH and the establishment of quality standards.
Keyphrases
- tandem mass spectrometry
- liquid chromatography
- ultra high performance liquid chromatography
- ms ms
- high performance liquid chromatography
- simultaneous determination
- high resolution mass spectrometry
- mass spectrometry
- gas chromatography
- solid phase extraction
- electronic health record
- liquid chromatography tandem mass spectrometry
- drug delivery
- big data
- drug release
- high resolution
- cancer therapy
- small molecule
- data analysis
- high throughput
- artificial intelligence