Predictors and clinical impact of infarct progression rate in the ESCAPE-NA1 trial.
Johanna Maria OspelRosalie McDonoughAndrew M DemchukBijoy K MenonMohammed A AlmekhlafiRaul G NogueiraRyan A McTaggartAlexandre Y PoppeBrian H BuckDaniel RoyDiogo C HaussenRené ChapotThalia S FieldMahesh V JayaramanMichael TymianskiMichael D HillMayank Goyalnull nullPublished in: Journal of neurointerventional surgery (2021)
In this sample of patients presenting within the early time window with LVO and near-complete recanalization, infarct progression rate was significantly associated with good outcome. A significant association between ASPECTS, collateral status, blood glucose, and NIHSS score was observed, but baseline imaging and clinical characteristics explained only a small proportion of the interindividual variance. More research on measurable factors affecting infarct growth is needed.
Keyphrases
- blood glucose
- acute myocardial infarction
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- high resolution
- prognostic factors
- glycemic control
- type diabetes
- patient reported outcomes
- phase iii
- metabolic syndrome
- phase ii
- blood pressure
- case report
- mass spectrometry
- acute coronary syndrome
- coronary artery disease
- middle cerebral artery
- percutaneous coronary intervention
- adipose tissue
- atrial fibrillation
- open label
- patient reported
- insulin resistance