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Predictors of relapse, death or heart transplantation in myocarditis before the introduction of immunosuppression: negative prognostic impact of female gender, fulminant onset, lower ejection fraction and serum autoantibodies.

Anna BaritussioAlessandro SchiavoCristina BassoAndrea Silvio GiordaniChun-Yan ChengElena PontaraMaria Grazia CattiniElisa BisonNicoletta GalloMonica De GaspariElisa CarturanGaetano ThieneGiuseppe TarantiniMario PlebaniStefania RizzoDario GregoriSabino IlicetoRenzo MarcolongoAlida Linda Patrizia Caforio
Published in: European journal of heart failure (2022)
Young age and a previous myocarditis were independent relapse predictors; female gender, fulminant onset, lower LVEF at presentation and high-titre organ-specific AHA and ANA were independent predictors of death and HTx, suggesting that autoimmune features predict worse prognosis.
Keyphrases
  • ejection fraction
  • aortic stenosis
  • mental health
  • systemic lupus erythematosus
  • free survival
  • liver failure
  • coronary artery disease