Predictors of relapse, death or heart transplantation in myocarditis before the introduction of immunosuppression: negative prognostic impact of female gender, fulminant onset, lower ejection fraction and serum autoantibodies.
Anna BaritussioAlessandro SchiavoCristina BassoAndrea Silvio GiordaniChun-Yan ChengElena PontaraMaria Grazia CattiniElisa BisonNicoletta GalloMonica De GaspariElisa CarturanGaetano ThieneGiuseppe TarantiniMario PlebaniStefania RizzoDario GregoriSabino IlicetoRenzo MarcolongoAlida Linda Patrizia CaforioPublished in: European journal of heart failure (2022)
Young age and a previous myocarditis were independent relapse predictors; female gender, fulminant onset, lower LVEF at presentation and high-titre organ-specific AHA and ANA were independent predictors of death and HTx, suggesting that autoimmune features predict worse prognosis.