Treatment response in acute myeloid leukaemia-Clues in the biopsy core.

Alicia G Aguilar NavarroAnastasia N Tikhonova

Published in: British journal of haematology (2022)

In their paper the authors describe distinct transcriptomic changes associated to treatment response in core bone marrow biopsies from patients with acute myeloid leukaemia. This finding raises the possibility that stratifying patients for treatment according to their transcriptomic profiles could improve patients' response and prognosis. Commentary on: Treaba et al. Transcriptomics of AML core bone marrow biopsies reveals distinct therapy response-specific osteo-mesenchymal profiles. Br J Haematol 2022 (Online ahead of print). doi: 10.1111/bjh.18513.

Keyphrases

bone marrow
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
acute myeloid leukemia
mesenchymal stem cells
single cell
peritoneal dialysis
prognostic factors
dendritic cells
social media
intensive care unit
patient reported
aortic dissection