Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells.

Shengyu WuXiaolu ZhuBiechuan GuoTian ZhengJiangbo RenWen ZengXiaomin ChenMin Ke

Published in: Journal of ophthalmology (2019)

The 3 UPR-mediated inflammatory pathways were dependent on each other. Inhibition any of these signaling pathways in UPR might be a potential therapeutic target for DR.

Keyphrases

endoplasmic reticulum
induced apoptosis
oxidative stress
signaling pathway
endoplasmic reticulum stress
cell cycle arrest
optical coherence tomography
diabetic retinopathy
pi k akt
editorial comment
epithelial mesenchymal transition
risk assessment
protein protein
optic nerve
human health