Changes in hepatocellular carcinoma aggressiveness characteristics with an increase in tumor diameter.
Brian I CarrVito GuerraRossella DonghiaFabio FarinatiEdoardo G GianniniFabio PiscagliaGian Ludovico RapacciniMaria Di MarcoEugenio CaturelliMarco ZoliRodolfo SaccoGiuseppe CabibboFabio MarraAndrea MegaFilomena MoriscoAntonio GasbarriniGianluca Svegliati-BaroniFrancesco Giuseppe FoschiGabriele MissaleAlberto MasottoGerardo NardoneGiovanni RaimondoFrancesco AzzaroliGianpaolo VidiliFilippo OliveriFranco TrevisaniPublished in: The International journal of biological markers (2021)
The greater fold-increases in alpha-fetoprotein and portal vein thrombosis compared with increases in maximum tumor diameter imply that hepatocellular carcinoma characteristics may change with increasing size to a more aggressive phenotype, suggesting that follow-up tumor sampling might be useful, in addition to baseline tumor sampling, for optimal therapeutic choices to be made.
Keyphrases