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Exenatide once weekly slows gastric emptying of solids and liquids in healthy, overweight people at steady-state concentrations.

Karen Louise JonesLian Q HuynhSeva HatzinikolasRachael S RigdaLiza K PhillipsHung T PhamChinmay S MaratheChinmay S MaratheCharles H MalbertJulie E StevensKylie LangeChristopher K RaynerMichael Horowitz
Published in: Diabetes, obesity & metabolism (2020)
In healthy participants, 8 weeks' administration of the "long-acting" glucagon-like peptide-1 receptor agonist EXE, slowed gastric emptying of solids and liquids substantially, with consequent reductions in glucose absorption and postprandial glycaemia.
Keyphrases
  • blood glucose
  • weight loss
  • physical activity
  • blood pressure
  • gestational age
  • adipose tissue
  • skeletal muscle
  • glycemic control