Systematic review with meta-analysis: biologics and risk of infection or cancer in elderly patients with inflammatory bowel disease.

Daniele Piovani Silvio Danese Laurent Peyrin Biroulet Georgios K Nikolopoulos Stefanos Bonovas

Published in: Alimentary pharmacology & therapeutics (2020)

Biologics are likely to increase the risk of serious and opportunistic infections in old IBD patients. Large prospective studies are needed to further assess the biologic treatments' long-term safety profile in this population.

Keyphrases

end stage renal disease
patients with inflammatory bowel disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
papillary thyroid
prognostic factors
patient reported outcomes
community dwelling