Rhodium catalysed intramolecular benzannulation for the formation of tetracyclic carbazoles.

Y Bharath Chaithanya KumarPolasani SamathaPrathama S Mainkar Raju Adepu

Published in: Organic & biomolecular chemistry (2022)

Rhodium catalyzed alkyne-tethered intramolecular annulation has been demonstrated for the synthesis of tetracyclic carbazole skeletons and a series of five to eight-membered pyrido[3,2,1- jk ]carbazoles were successfully obtained. The present atom economical annulation proceeded under mild reaction conditions, offering a broad substrate scope.

Keyphrases

energy transfer
electron transfer
molecular dynamics
room temperature
amino acid
structural basis