The Association Between Clozapine Plasma Concentration, CYP2D6 (10, 2) Polymorphisms and Risk of Adverse Reactions.

Zhongdong Zhang Qin Zhou Haohao Zhu Zhenhe Zhou Yuan Shen Lin Tian Xujiang Su

Published in: Psychiatry and clinical psychopharmacology (2023)

This study demonstrated that the determination of cytochrome P450 2D6 polymorphisms and therapeutic drug monitoring of clozapine might be beneficial for identifying patients with a higher risk of adverse reactions.

Keyphrases

adverse drug
emergency department
solid phase extraction
molecularly imprinted
mass spectrometry