Genome-Wide Association Screens for Anterior Cruciate Ligament Tears.

Vincenzo Candela Umile Giuseppe LongoAlessandra BertonGiuseppe SalvatoreFrancisco ForriolAlessandro de SireVincenzo Denaro

Published in: Journal of clinical medicine (2024)

Findings regarding the association between genes encoding for collagen (COL3A1, COL1A1, and COL12A1), aggrecan (ACAN), decorin (DCN), matrix metalloproteinase (MMP3), interleukin 6 (IL-6), vascular endothelial growth factor A (VEGFA), biglycan (BGN), fibrinogen (FGB), and ACL injuries were found to be inconclusive. Additional evidence is required in order to establish substantial conclusions regarding the association between genetic variants and ACL rupture.

Keyphrases

vascular endothelial growth factor
anterior cruciate ligament
genome wide association
genome wide
endothelial cells
high throughput
rotator cuff
gene expression
genome wide identification
tissue engineering