A cluster of scedosporiosis in lung transplant candidates and recipients: The Zurich experience and review of the literature.
Irene A AbelaChristian MurerMacé Matthew SchuurmansJuergen W SchmittFrabci MullerFrank ImkampNicolas J MuellerChristian BendenPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2017)
Scedosporium species are fungal pathogens increasingly recognized in cystic fibrosis (CF). They can cause multiresistant, life-threatening infections that are of particular concern in CF patients undergoing lung transplantation, as optimal treatment remains unclear. Here, we describe our Zurich experience of CF patients with Scedosporium infection. Disseminated infection occurred in one patient after transplantation and was successfully treated. We propose a step-by-step approach to treat candidates with colonization, and discuss our cases in the context of the current literature.