Real-time laser speckle contrast imaging measurement during normothermic machine perfusion in pretransplant kidney assessment.

Yitian FangLisanne van OoijenGisela AmbagtsheerAnton V NikolaevMarian C Clahsen-van GroningenJenny DankelmanRon W F de BruinRobert C Minnee

Published in: Lasers in surgery and medicine (2023)

LSCI fluxes correlated linearly with renal blood flow during NMP. Renal cortical microcirculation and absent perfusion can be visualized and semiquantified by LSCI. It provides a relative understanding of perfusion levels, allowing for a qualitative comparison between regions in the kidney. Dual-side LSCI measurements are of added value compared to single aspect measurement and renal function markers.

Keyphrases

blood flow
contrast enhanced
magnetic resonance
magnetic resonance imaging
high resolution
deep learning
mass spectrometry
clinical evaluation