Comparison of a rapid point-of-care and two laboratory-based CYP2C19*2 genotyping assays for personalisation of antiplatelet therapy.

Francesca WirthGraziella ZahraRobert G XuerebChristopher BarbaraAlbert FenechLilian M Azzopardi

Published in: International journal of clinical pharmacy (2016)

Compared to both laboratory-based genotyping assays, the POC assay is accurate and reliable, provides rapid results, can process single samples, is portable and more operator-friendly, however the tests are more expensive.

Keyphrases

high throughput
antiplatelet therapy
acute coronary syndrome
percutaneous coronary intervention
loop mediated isothermal amplification
single cell
genome wide
low cost
high resolution
coronary artery disease
gene expression
genetic diversity
atrial fibrillation
sensitive detection
mass spectrometry