Whole exome sequencing identifies multiple novel candidate genes in familial gastroschisis.

Víctor M Salinas-TorresHugo L Gallardo-BlancoRafael A Salinas-TorresRicardo M Cerda-FloresJosé J Lugo-TrampeDaniel Z Villarreal-MartínezMarisol Ibarra-RamírezLaura E Martínez de Villarreal

Published in: Molecular genetics & genomic medicine (2020)

Considering the likely gene-disrupting prediction results and similar biological pattern of mechanisms, we propose a joint "multifactorial model" in gastroschisis pathogenesis.

Keyphrases

genome wide
copy number
early onset
genome wide identification
transcription factor