Bioinformatic Identification of Hub Genes Related to Menopause-Obesity Paradox in Breast Cancer.
Zahra HosseinpourMostafa Rezaei TaviraniMohammad Esmaeel AkbariPublished in: International journal of endocrinology and metabolism (2023)
These results may improve our understanding of the underlying mechanisms of the effects of body mass on BC and assist in identifying biomarkers and potential therapeutic targets for treating obese postmenopausal women with BC.
Keyphrases
- bioinformatics analysis
- weight loss
- metabolic syndrome
- type diabetes
- insulin resistance
- adipose tissue
- bone mineral density
- postmenopausal women
- bariatric surgery
- high fat diet induced
- weight gain
- genome wide
- obese patients
- human health
- gene expression
- network analysis
- body mass index
- dna methylation
- risk assessment
- transcription factor
- skeletal muscle