A liver-specific gene expression panel predicts the differentiation status of in vitro hepatocyte models.

Dae-Soo KimJea-Woon RyuMi-Young SonJung-Hwa OhKyung-Sook ChungSugi LeeJeong-Ju LeeJun-Ho AhnJu-Sik MinJiwon AhnHyun Mi KangJanghwan KimCho-Rok JungNam-Soon KimHyun-Soo Cho

Published in: Hepatology (Baltimore, Md.) (2017)

Our study describes a quantitative and predictive model for differentiated samples, particularly liver-specific cells or organoids; and this model can be further expanded to various tissue-specific organoids; our LiGEP can provide useful information and insights regarding the differentiation status of in vitro liver models. (Hepatology 2017;66:1662-1674).

Keyphrases

gene expression
induced apoptosis
dna methylation
cell cycle arrest
health information
social media
induced pluripotent stem cells