Machine learning based on Optical Coherence Tomography images as a diagnostic tool for Alzheimer's disease.

Xin WangBin JiaoHui LiuYaqin WangXiaoli HaoYuan ZhuBei XuHuizhuo XuSizhe ZhangXiaoliang JiaQian Xu Xinxin LiaoYafang ZhouJiang Hong Jun-Ling Wang Ji-Feng GuoXinxiang YanBeisha TangRongchang ZhaoLu Shen

Published in: CNS neuroscience & therapeutics (2022)

We identified the retinal alterations in AD patients and found that macular thickness and volume were associated with AD severity and biomarkers. Furthermore, we confirmed that OCT combined with ML could serve as a potential diagnostic tool for AD.

Keyphrases

optical coherence tomography
diabetic retinopathy
machine learning
end stage renal disease
optic nerve
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
deep learning
cognitive decline
big data
patient reported
mild cognitive impairment
convolutional neural network