Intracranial pressure and optic disc changes in a rat model of obstructive hydrocephalus.
Snorre Malm HagenSajedeh EftekhariSteffen HamannMarianne JuhlerRigmor Hoejland JensenPublished in: BMC neuroscience (2022)
We demonstrated that the raised ICP at day 1 in the hydrocephalus animals was completely normalized within 1 week and that epidural ICP measurements are valid method in this model. No acute papilledema was identified in the hydrocephalus animals, but the peripapillary changes indicate a potential gliosis formation or an early state of a growing papilledema in the context of lateral ventricle dilation and increased ICP.
Keyphrases
- subarachnoid hemorrhage
- cerebrospinal fluid
- optic nerve
- optical coherence tomography
- liver failure
- brain injury
- spinal cord
- pulmonary hypertension
- mitral valve
- respiratory failure
- pulmonary artery
- minimally invasive
- heart failure
- drug induced
- aortic dissection
- clinical trial
- pulmonary arterial hypertension
- congenital heart disease
- hepatitis b virus
- human health