A Stress Protein Based Suicide Prediction Score and relationship to reported Early Life Adversity and Recent Life Stress.

Mark D UnderwoodHanga GalfalvyShu-Chi HsiungYan LiuNorman R SimpsonMihran J BakalianGorazd B RosoklijaAndrew J DworkVictoria ArangoJ John Mann

Published in: The international journal of neuropsychopharmacology (2023)

A dysregulated HPA axis is related to suicide but not with ELA. RLS was related to select HPA axis proteins in specific brain regions. BDNF appears dysregulated in a region-specific way with ELA and suicide.

Keyphrases

early life
stress induced
white matter
resting state
binding protein
multiple sclerosis
amino acid
cerebral ischemia