Neurocognitive impact of Zika virus infection in adult rhesus macaques.

Denise C HsuKesara ChumpolkulwongMichael J CorleyTaweewun HunsawongDutsadee InthawongAlexandra SchuetzRawiwan ImerbsinDecha SilsornPanupat NadeeJumpol SopanapornYuwadee Phuang-NgernChonticha KlungthongMatthew ReedStefan FernandezLishomwa C NdhlovuRobert PaulLuis Lugo-RomanNelson L MichaelKayvon ModjarradSandhya Vasan

Published in: Journal of neuroinflammation (2022)

The co-occurrence of systemic and CSF immune perturbations and neurocognitive impairment establishes this model as useful for studying the impact of neuroinflammation on neurobehavior in rhesus macaques, as it pertains to ZIKV infection and potentially other pathogens.

Keyphrases

bipolar disorder
zika virus
traumatic brain injury
lipopolysaccharide induced
gram negative
lps induced
cognitive impairment
inflammatory response
cerebral ischemia
childhood cancer
cerebrospinal fluid
young adults