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Tendon Transection Healing Can Be Improved With Adipose-Derived Stem Cells Cultured With Growth Differentiation Factor 5 and Platelet-Derived Growth Factor.

Michael J FitzgeraldTaylor MustapichHaixiang LiangChristopher G LarsenKate W NellansDaniel A Grande
Published in: Hand (New York, N.Y.) (2021)
Adipose-derived stem cells cultured with GDF5/PDGF prior to implantation can promote tendon repair by improving cellular proliferation, tenogenesis, and vascular infiltration. This effect results in a greater degree of organized tendon healing.
Keyphrases
  • growth factor
  • anterior cruciate ligament reconstruction
  • rotator cuff
  • endothelial cells
  • signaling pathway
  • wound healing
  • vascular smooth muscle cells