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L-asparaginase and 6-diazo-5-oxo-L-norleucine synergistically inhibit the growth of glioblastoma cells.

Shigeo OhbaYuichi Hirose
Published in: Journal of neuro-oncology (2020)
The results suggest that the combination of L-asparaginase and DON could be a new therapeutic option for patients with glioblastoma.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • cell death
  • pi k akt