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Functional connectome contractions in temporal lobe epilepsy: Microstructural underpinnings and predictors of surgical outcome.

Sara LariviereYifei WengReinder Vos de WaelJessica RoyerBirgit FrauscherZhengge WangAndrea BernasconiNeda BernasconiDewi V SchraderZhiqiang ZhangBoris C Bernhardt
Published in: Epilepsia (2020)
Our findings suggest connectivity distance contractions as a macroscale substrate of TLE. Functional topological isolation may represent a microstructurally mediated network mechanism that tilts the balance toward epileptogenesis in affected networks and that may assist in patient-specific surgical prognostication.
Keyphrases
  • temporal lobe epilepsy
  • white matter
  • resting state
  • functional connectivity
  • network analysis