CpG island turnover events predict evolutionary changes in enhancer activity.
Acadia A KocherEmily V DutrowSeverin UebbingKristina M YimMaría F Rosales LariosMarybeth BaumgartnerTimothy NottoliJames P NoonanPublished in: Genome biology (2024)
Collectively, our results point to CGI turnover as a mechanism driving gene regulatory changes potentially underlying trait evolution in mammals.