What is the appropriate genetic testing criteria for breast cancer in the Chinese population?-Analysis of genetic and clinical features from a single cancer center database.
Mengqian NiFang WangAnli YangQiong ShaoCong XueWen XiaFei XuXi LinJiajia HuangXiwen BiRuoxi HongMei-Ting ChenQiufan ZhengKuikui JiangXinhua XieJun TangXi WangZhongyu YuanShu-Sen WangYanxia ShiXin AnPublished in: Cancer medicine (2023)
Desai's criteria might be a more appropriate genetic testing strategy for Chinese BC patients. Panel testing could identify more non-BRCA P/LPVs than BRCA1/2 testing alone. Compared with BRCA1/2 P/LPVs, non-BRCA P/LPVs exhibited different personal and family histories of cancer and molecular subtype distributions. The optimal genetic testing strategy for BC still needs to be investigated with larger continuous population studies.
Keyphrases
- papillary thyroid
- breast cancer risk
- end stage renal disease
- squamous cell
- ejection fraction
- newly diagnosed
- chronic kidney disease
- childhood cancer
- lymph node metastasis
- squamous cell carcinoma
- young adults
- atomic force microscopy
- peritoneal dialysis
- patient reported outcomes
- copy number
- high resolution
- high speed