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High-Dose Dexmedetomidine Promotes Apoptosis in Fetal Rat Hippocampal Neurons.
Qiufeng Wei
Jing Chen
Fei Xiao
Youbing Tu
Yu Zhong
Yu-Bo Xie
Published in:
Drug design, development and therapy (2021)
High concentrations of dexmedetomidine produced toxic effects on neurons and caused neuronal apoptosis.
Keyphrases
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oxidative stress
high dose
endoplasmic reticulum stress
cell cycle arrest
spinal cord
cell death
cardiac surgery
cerebral ischemia
low dose
stem cell transplantation
acute kidney injury
spinal cord injury
cell proliferation
signaling pathway
blood brain barrier