Metabolomics and Biomarkers for Paroxysmal and Persistent Atrial Fibrillation.

Li-Li ZhangWen-Hua LinCheng-Ye DiHai-Tao HouHuan-Xin Chen Jie Zhou Qin Yang Guo-Wei He

Published in: Journal of the American Heart Association (2024)

In this metabolomics study, we detected 36 differential metabolites in AF, and 4 were validated with high sensitivity and specificity. These differential metabolites are potential biomarkers for diagnosis and monitoring of disease course. This study therefore provides new insights into the precision diagnosis and management of AF.

Keyphrases

atrial fibrillation
mass spectrometry
heart failure
left atrial appendage
mitral valve