Genome Engineering Renal Epithelial Cells for Enhanced Volume Transport Function.

Matthew H WilsonRuth Ann VeachWentian LuoRichard C WelchShuvo RoyWilliam H Fissell

Published in: Cellular and molecular bioengineering (2019)

Our results demonstrate that renal epithelial cells an be genome engineered for enhanced volumetric transport that will be needed for an IAK device. Our results lay the foundation for future studies of genome engineering human kidney cells for renal tubule cell therapy.

Keyphrases

cell therapy
genome wide
endothelial cells
induced apoptosis
stem cells
mesenchymal stem cells
gene expression
bone marrow
cell proliferation
signaling pathway
pi k akt