Interleukin-11 disrupts alveolar epithelial progenitor function.
Rosa K KortekaasKerstin E Geillinger-KästleTheo BorghuisKaoutar BelharchMegan WebsterHidde J HaismaJanette Kay BurgessReinoud GosensPublished in: ERJ open research (2023)
IL-11 disrupts alveolar epithelial regeneration by inhibiting progenitor activation and suppressing the formation of mature alveolar epithelial cells. Evidence for a contribution of dysregulated fibroblast-epithelial communication to this process is limited.
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