Decreased Intracranial Pressure Elevation and Cerebrospinal Fluid Outflow Resistance: A Potential Mechanism of Hypothermia Cerebroprotection Following Experimental Stroke.
Daniel OmilekeSteven W BothwellDebbie PepperallDaniel J BeardKirsten CouplandAdjanie PatabendigeNeil J SprattPublished in: Brain sciences (2021)
Hypothermia treatment was protective in terms of ICP rise prevention, infarct volume reduction, and may be implicated in CSF outflow resistance post-stroke. Further investigations are warranted to elucidate the mechanisms of ICP elevation and hypothermia treatment.