Kappa Free Light Chain Drift Prompts the Need for a New Upper Limit of Normal Free Light Chain Ratio to Avoid an Epidemic of Kappa Light Chain Monoclonal Gammopathy of Undermined Significance.
Krasimira A RozenovaMaria Alice Vieira WillrichMelissa SnyderSurendra DasariTaxiarchis KourelisS Vincent RajkumarShaji KumarAngela DispenzieriDavid L MurrayPublished in: The journal of applied laboratory medicine (2023)
The results of this study suggest decreased specificity of rFLC for a monoclonal kappa FLC in the 1.65 to 3.0 range.