Login / Signup

The inhibition of MDM2 slows cell proliferation and activates apoptosis in ADPKD cell lines.

Simone PatergnaniAntonino GiattinoNicoletta BianchiCarlotta GiorgiPaolo PintonGianluca Aguiari
Published in: Biology of the cell (2022)
The targeting of MDM2 by RG7112 might represent a new therapeutic option for the treatment of ADPKD.
Keyphrases
  • cell proliferation
  • polycystic kidney disease
  • oxidative stress
  • endoplasmic reticulum stress
  • cell death
  • cell cycle arrest
  • cell cycle
  • cancer therapy
  • pi k akt