Sonicate Fluid Cellularity Predicted by Transcriptomic Deconvolution Differentiates Infectious from Non-Infectious Arthroplasty Failure.

Cody R Fisher Jordan Edward Krull Aditya Bhagwate Thao Masters Kerryl E Greenwood-Quaintance Matthew P Abdel Robin Patel

Published in: The Journal of bone and joint surgery. American volume (2022)

CIBERSORTx can predict the cellularity of sonicate fluid using transcriptomic data, allowing for the evaluation of the underlying immune response during the PJIF and NIAF cases, without a need to phenotypically assess cell composition.

Keyphrases

single cell
immune response
rna seq
cell therapy
electronic health record
big data
dendritic cells
toll like receptor
machine learning
mesenchymal stem cells
data analysis