Exploring the link between blood pressure variability and atrial fibrillation: current insights and future directions.
Konstantinos KonstantinouAnastasios ApostolosDimitrios TsiachrisKyriakos DimitriadisPanteleimon E PapakonstantinouKonstantinos PappelisVasileios PanoulasKonstantinos P TsioufisPublished in: Journal of human hypertension (2024)
Atrial fibrillation (AF) is the most common heart rhythm disorder, especially in people over the age of 50, which affects more than 40 million people worldwide. Many studies have highlighted the association between hypertension with the development of AF. Blood pressure variability (BPV) is a dynamic size obtained by recording blood pressure oscillations using specific readings and at specific time intervals. A multitude of internal and external factors shape BPV while at the same time constituting a common pathogenetic pathway with the development of AF. Until recently, BPV has been applied exclusively in preclinical and clinical studies, without significant implications in clinical practice. Indeed, even from the research side, the determination of BPV is limited to patients without AF due to doubts about the accuracy of its measurement methods in patients with AF. In this review, we present the current evidence on common pathogenic pathways between BPV and AF, the reliability of quantification of BPV in patients with AF, the prognostic role of BPV in these patients, and discuss the future clinical implications of BPV in patients with AF.
Keyphrases
- atrial fibrillation
- blood pressure
- oral anticoagulants
- left atrial
- catheter ablation
- end stage renal disease
- left atrial appendage
- direct oral anticoagulants
- heart failure
- newly diagnosed
- percutaneous coronary intervention
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- heart rate
- prognostic factors
- clinical practice
- stem cells
- hypertensive patients
- skeletal muscle
- metabolic syndrome
- venous thromboembolism
- mass spectrometry
- blood glucose
- insulin resistance
- adipose tissue
- simultaneous determination